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(klor-HEX-ih-deen GLUE-koe-nate)
Bactoshield, Bactoshield 2, Betasept, Dyna-Hex 2 Skin Cleanser, Dyna-Hex Skin Cleanser, Exidine-2 Scrub, Exidine-4 Scrub Care, Exidine Skin Cleanser, Hibiclens, Hibiclens Antiseptic/Antimicrobial Skin Cleanser, Hibistat, Hibistat Germicidal Hand Rinse, Hibistat Towelettes, Peridex, PerioChip, PerioGard,  Hexifoam, Hibidil, Hibitane, Spectro Gram
Class: Antiseptic/germicide

 Action Provides antimicrobial effect against a wide range of microorganisms.

 Indications Surgical scrub; skin cleanser; preoperative skin preparation; skin wound cleanser; hand rinse; oral rinse for gingivitis; an adjunct to scaling and root planning procedures for reduction of pocket depth in adults with periodontitis. Unlabeled use(s): Treatment of acne vulgaris. Amelioration of oral mucositis associated with cytoreductive therapy for bone marrow transplant candidates.

 Contraindications Standard considerations.

 Route/Dosage

Skin Use

5 ml is applied to skin and worked into lather.

Periodontitis

2.5 mg (1 chip) inserted into periodonted pocket with probing depth ³ 5 mm.

Oral Rinse for Gingivitis

15 ml (1 capful) bid for 30 seconds, morning and evening after toothbrushing. Expectorate after rinsing; do not swallow.

 Interactions None well documented.

 Lab Test Interferences None well documented.

 Adverse Reactions

DERM: Irritation; dermatitis; photosensitivity; sensitization and generalized allergic reactions, especially in genital area. EENT: Deafness; transient parotitis, altered taste perception. OTHER: Staining of teeth and oral surfaces; increased calculus formation; minor irritation and superficial desquamation of oral mucosa.

 Precautions

Pregnancy: Category B (oral rinse). Pregnancy category undetermined for skin use. Lactation: Undetermined.

PATIENT CARE CONSIDERATIONS

 Administration/Storage

  • For surgical wash, scrub, or bacteriostatic cleansing: wet hands with warm water and squeeze 5 ml into palm, add water, work up lather, apply lather to area being cleansed and rinse thoroughly.
  • For oral rinse: swish in mouth for 30 seconds after toothbrushing and expectorate.
  • For surgical hand scrub: wet hands and use nail cleaner under fingernails and to clean cuticles. Wet hands and forearms to elbows with warm water, apply lather, scrub for 3 minutes and rinse thoroughly. Scrub for additional 3 minutes, rinse and dry hands and forearms with sterile towel.
  • Keep medication out of ears, eyes and mouth. Serious and permanent eye injury and deafness may occur if used improperly.
  • Do not use this medication routinely on wounds involving more than superficial layers of skin.
  • Avoid contact with meninges.
  • Do not freeze.
  • Store at room temperature. (PerioChip should be stored in the refrigerator.)
  • Prolonged direct exposure to strong light may cause brownish surface discoloration but does not affect action.
  • Shake to disperse color.

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Monitor for allergic reactions (urticaria, bronchospasm, cough, shortness of breath).
  • Monitor skin and mouth for irritation.
OVERDOSAGE: SIGNS & SYMPTOMS
  Gastric distress, alcohol intoxication

 Patient/Family Education

  • Inform patient that staining of teeth, dental work, tongue and oral tissue may occur. Staining does not adversely affect health and can usually be removed by professional techniques.
  • Caution patient that taste perception may be altered during treatment; permanent taste alteration has not been noted.
  • Inform patient that oral rinse contains alcohol.
  • Instruct patient to avoid having medication come into contact with ears and eyes, which could cause permanent damage.
  • Instruct patient not to swallow product but to expectorate after oral rinsing.
  • Advise patient to avoid eating 2–3 hr after treatment.
  • Advise patients to avoid dental floss at the site of chip insertion for 10 days after placement because flossing might dislodge the chip.
  • Instruct patient to notify dentist promptly if chip dislodges.
  • Advise patient that although mild to moderate sensitivity is normal during the first week after placement of the chip, notify dentist if pain, swelling, or other problems occur.

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