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| (klor-ZOX-uh-zone) |
| Paraflex, Parafon Forte DSC, Remular-S |
| Class: Skeletal muscle relaxant/Centrally acting |
Action Action may be related to its sedative properties or to inhibition of reflex arcs at spinal cord and subcortical levels of brain.
Indications Relief of discomfort associated with painful musculoskeletal conditions.
Contraindications Standard considerations.
ADULTS: PO Initial (for acute pain): 500 mg tid-qid; increase to 750 mg if needed. As improvement occurs, reduce dose; 250 mg tid-qid is usually sufficient.
Alcohol and other CNS depressants: Additive CNS depressant effects may occur.
Lab Test Interferences None well documented.
CNS: Drowsiness; dizziness; lightheadedness; malaise; overstimulation. DERM: Allergic-type skin rashes; petechiae. GI: GI disturbances. GU: Urine discoloration (orange or purple red). HEPA: Drug-induced hepatitis. OTHER: Hypersensitivity (eg, angioneurotic edema; anaphylaxis).
Pregnancy: Pregnancy category undetermined. Lactation: Undetermined. Hepatic impairment: Avoid use in patients with liver impairment; discontinue if signs of dysfunction occur. Hazardous tasks: May impair ability to perform tasks requiring mental or physical coordination or dexterity, including driving. Drowsiness is very common.
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