Dextromethorphan Hydrobromide

(DEX-troe-meth-OR-fan HIGH-droe-BROE-mide)
Benylin Adult
Liquid
15 mg/5 mL
Benylin DM
Syrup
10 mg/5 mL
Benylin Pediatric
Liquid
7.5 mg/5 mL
Children’s Hold
Lozenges
5 mg
Creo-Terpin
Liquid
10 mg/15 mL (3.33 mg/ 5 mL)
Delsym
Liquid, sustained-action
Dextromethorphan polistirex equivalent to 30 mg dextromethorphan HBr/5 mL.
Diabetes CF
Syrup
10 mg/5 mL
Drixoral Cough Liquid Caps
Capsules
30 mg
Hold DM
Lozenges
5 mg
Pediatric Vicks 44d Dry Hacking Cough and Head Congestion
Syrup
15 mg/15 mL (1 mg/mL
Pertussin CS
Liquid 3.5 mg/5 mL
Pertussin ES
Liquid
15 mg/5 mL
Robitussin Cough Calmers
Lozenges
5 mg
Robitussin Pediatric
Liquid
7.5 mg/5 mL
Scot-Tussin DM Cough Chasers
Lozenges
2.5 mg
Silphen DM
Syrup
10 mg/5 mL
St. Joseph Cough Suppressant
Liquid
7.5 mg/5 mL
Sucrets 4-hr Cough
Lozenges
15 mg
Sucrets Cough Control
Lozenges
5 mg
Suppress
Lozenges
7.5 mg
Trocal
Lozenges
7.5 mg
Vicks Dry Hacking Cough
Liquid
15 mg/5 mL
Balminil DM, Balminil DM Children, Benylin DM, Benylin DM for Children, Delsym, Koffex DM, Koffex DM Children, Robitussin Pediatric, Triaminic DM
Class: Antitussive, Nonnarcotic

 Action Suppresses cough by central action on cough center in medulla.

 Indications Management of nonproductive cough.

 Contraindications Standard considerations.

 Route/Dosage

Gelcaps Adults and children (at least 12 yr): PO 30 mg q 6 to 8 hr (max, 120 mg/day).

Lozenges Adults and children (at least 12 yr) PO 5 to 15 mg q 1 to 4 hr (max, 120 mg/day).

Children (6 to under 12 yr): PO 5 to 10 mg q 1 to 4 hr (max, 60 mg/day).

Liquid and syrup Adults and children (at least 12 yr): PO 10 to 20 mg q 4 hr or 30 mg q 6 to 8 hr (max, 120 mg/day).

Children (6 to under 12 yr): PO 15 mg q 6 to 8 hr (max, 60 mg/day).

Children (2 to under 6 yr): PO 7.5 mg q 6 to 8 hr (max, 30 mg/day).

Extended-release suspension Adults and children (at least 12 yr): PO 60 mg q 12 hr (max, 120 mg/day).

Children (6 to under 12 yr): PO 30 mg q 12 hr (max, 60 mg/day).

Children (2 to under 6 yr): PO 15 mg q 12 hr (max, 30 mg/day).

 Interactions

MAO Inhibitors: Hypotension, hyperpyrexia, nausea, myoclonic jerks, and coma may develop after coadministration.

 Lab Test Interferences None well documented.

 Adverse Reactions

Nausea, drowsiness, dizziness.

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Chronic cough: Do not use for persistent or chronic cough (eg, smoking, asthma, emphysema) or when cough is accompanied by excessive secretions. People with high fever, rash, persistent headache, nausea, or vomiting should use only under medical supervision. Drug abuse and dependence: Anecdotal reports of abuse have increased. However, abuse and dependency potential is undetermined.

PATIENT CARE CONSIDERATIONS

 Administration/Storage

  • Store liquids, lozenges, and syrups at room temperature and out of reach of children.

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies. Note any respiratory problems and smoking history.
  • Assess type of cough (dry or productive), severity, and progression.
  • Assess baseline vital signs including fever.
  • Do not administer for persistent or chronic cough, longer than 7 days, or when cough is accompanied by excessive secretions.
  • Monitor blood glucose levels in diabetic patients.
OVERDOSAGE: SIGNS & SYMPTOMS
  Ataxia, respiratory depression, convulsions (children); altered sensory perception, dysphoria, slurred speech (adults)

 Patient/Family Education

  • Alert patient that many products contain alcohol.
  • Instruct patient to notify health care provider before taking medication with other prescriptions (eg, MAOIs).
  • Inform diabetic patients that base may contain sucrose or other sugars.
  • Encourage increased fluid intake to thin secretions.
  • Teach patients how to cough and breathe deeply to maximize respiratory efforts.
  • Explain to parents not to give lozenges to young children.

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