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(diff-THEER-ee-uh/TET-ah-nus toxoids/ay-SELL-you-luhr per-TUSS-iss/hem-AHF-ill-us in-flew-EN-zuh vaccine)
TriHIBit
Injection
10 mcg
Haemophilus influenza type b purified capsular polysaccharide conjugated to 24 mcg inactivated tetanus toxoid, 6.7 Lf diphtheria toxoid, 5 Lf tetanus toxoid, 46.8 mcg pertussis antigens per 0.5 mL. Supplied as ActHIB (Haemophilus b conjugate vaccine [tetanus toxoids combined]) with Tripedia (diphtheria and tetanus toxoids and acellular pertussis vaccine absorbed [(DTaP]). For prescribing information, refer to the Haemophilus b Conjugate Vaccine monograph and the Diphtheria/Tetanus Toxoids/Acellular Pertussis Vaccine monograph.
Class: Vaccine

 Action DTaP: Diphtheria and tetanus toxoids induce antibodies against toxins made by Corynebacterium diphtheriae and Clostridium tetani. Pertussis vaccine: Protects against Bordetella pertussis. Haemophilus B conjugate vaccine: Induces active immunity against Hib infection.

 Indications Active immunization of children 15 to 18 mo who have previously been immunized against diphtheria, tetanus, and pertussis with 3 doses consisting of diphtheria and tetanus toxoids and whole cell pertussis or DTaP vaccine and 3 doses or fewer of ActHIB within the first year of life for the prevention of invasive diseases caused by Haemophilus influenzae type b or by diphtheria, tetanus, and pertussis. Do not administer to infants younger than 15 mo.

 Contraindications For prescribing information, refer to the Haemophilus b Conjugate Vaccine monograph and the Diphtheria/Tetanus Toxoids/Acellular Pertussis Vaccine monograph.

 Route/Dosage

IM Administer in outer aspect of the mid-thigh or deltoid, not into the gluteal area or other areas where there may be a nerve trunk. First, second, and third dose: at age 2, 4, and 6 mo immunize with ActHIB reconstituted with DTP or saline diluent (0.4% sodium chloride). Fourth dose: at 15 to 18 mo immunize with ActHIB reconstituted with DTP or Tripedia or with saline diluent (0.4% sodium chloride). Fifth dose: at 4 to 6 yr immunize with Tripedia or DTP. Vaccinate preterm infants according to their chronological age from birth.

 Interactions

For prescribing information, refer to the Haemophilus b Conjugate Vaccine monograph and the Diphtheria/Tetanus Toxoids/Acellular Pertussis Vaccine monograph.

 Adverse Reactions

For prescribing information, refer to the Haemophilus b Conjugate Vaccine monograph and the Diphtheria/Tetanus Toxoids/Acellular Pertussis Vaccine monograph.

 Precautions

For prescribing information, refer to the Haemophilus b Conjugate Vaccine monograph and the Diphtheria/Tetanus Toxoids/Acellular Pertussis Vaccine monograph.

PATIENT CARE CONSIDERATIONS

 Administration/Storage

  • For prescribing information, refer to the Haemophilus b Conjugate Vaccine monograph and the Diphtheria/Tetanus Toxoids/Acellular Pertussis Vaccine monograph.

 Assessment/Interventions

  • For prescribing information, refer to the Haemophilus b Conjugate Vaccine monograph and the Diphtheria/Tetanus Toxoids/Acellular Pertussis Vaccine monograph.

 Patient/Family Education

  • For prescribing information, refer to the Haemophilus b Conjugate Vaccine monograph and the Diphtheria/Tetanus Toxoids/Acellular Pertussis Vaccine monograph.

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