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(mass-OH-prah-KOLE)
Actinex
Cream
10%
Class: Topical
Antiproliferative

 Actions Thought to have antiproliferative activity against keratinocytes.

 Indications Topical treatment of actinic (solar) keratoses.

 Contraindications Standard considerations.

 Route/Dosage ADULTS: Topical Massage evenly into area containing actinic keratoses each morning and evening for 28 days.

Interactions None well documented.

Lab Test Interferences None well documented.

 Adverse Reactions

DERMATOLOGIC: Erythema; flaking; itching; dryness; edema; burning; soreness; bleeding; crusting; oozing; rash; skin irritation; stinging; tightness; tingling. EENT: Eye irritation.

 Precautions

Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established. Application: Occlusive dressings should not be used with this product. External use: This product is for external use only. Avoid contact with eyes and mucous membranes. Sulfite sensitivity: Use caution in sulfite-sensitive individuals; preparation contains bisulfites.

PATIENT CARE CONSIDERATIONS

 Administration/Storage

  • Before application, wash, rinse, and dry affected area.
  • Apply each morning and evening for 28 days. Gently and evenly massage into affected area.
  • Wash hands immediately after application.
  • Avoid contact with eyes or mucous membranes. If contact occurs, promptly flush eye or mucous membranes with water.
  • Do not cover with occlusive dressing.
  • Store at room temperature.

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Assess number and severity of lesions before beginning therapy and throughout use of medication.
  • Assess area after administration for local reactions such as redness, flaking, itching, dryness, swelling, continued burning, oozing, blistering or bleeding.
  • If adverse reactions occur, notify health care provider immediately.

 Patient/Family Education

  • Explain proper method of administration. Tell patient that temporary stinging or burning sensation is common but should disappear quickly.
  • Warn patient that medication may stain clothing or other fabrics.
  • Advise patient not to use makeup or other skin products without consulting health care provider.
  • Caution patient to avoid excessive exposure to sun.
  • Instruct patient to avoid taking any other medications unless prescribed by health care provider.

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