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(myoo-PIHR-oh-sin)
Bactroban
Class: Topical/anti-infective

 Action Inhibits bacterial protein synthesis.

 Indications Topical treatment of impetigo caused by Staphylococcus aureus, Staphylococcus pyogenes, Streptococci, and Bacillus hemolyticus.

 Contraindications Standard considerations.

 Route/Dosage

ADULTS: Topical Apply tid for 3–5 days.

 Interactions None well documented.

 Lab Test Interferences None well documented.

 Adverse Reactions

DERM: Burning; stinging; pain; rash; itching; contact dermatitis.

 Precautions

Pregnancy: Category B. Lactation: Undetermined. Hypersensitivity: Chemical irritation may occur.

PATIENT CARE CONSIDERATIONS

 Administration/Storage

  • Apply topically only; avoid contact with eyes and mucous membranes. Treated area may be covered with gauze dressing.
  • Wash hands before and after application.

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Assess for signs of superinfection (bacterial or fungal overgrowth of nonsusceptible organisms).
  • Assess for therapeutic response: decrease in size and number of lesions.
  • If a skin reaction develops, discontinue therapy, wash affected area and notify physician.

 Patient/Family Education

  • Warn the patient to avoid contact of drug with eyes and mucous membranes.
  • Instruct patient to wash hands before and after application.
  • Tell patient to inform physician if no improvement is seen within 3–5 days or if condition worsens.
  • Advise patient to keep fingernails well trimmed to prevent scratching.
  • Review with patient and family appropriate hygiene measures to prevent spread of impetigo.
  • Instruct patient to report these symptoms to physician: burning, stinging, pain, nausea, tenderness, swelling, rash, dry skin or increased exudate.

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