"Official medicines" is the best online drugstore.

World’s leading meds delivered to your door – and you don’t even need a prescription! Only certified, first class drugs on offer! Buy more and spend less with our great discount system.

The meds you need, reliable and hassle free! Top products of top brands.

The only pharmacy shop you will ever need! Approved drugs available without prescription. Best deals, unmatched service and shipping. 100% safe!


(ore-FEN-uh-dreen SIH-trate)
Banflex, Flexoject, Flexon, Norflex
Class: Skeletal muscle relaxant/centrally acting

 Action Unknown; may be related to analgesic properties since drug acts on brain stem and does not act directly on muscles; possesses anticholinergic actions.

 Indications Adjunctive treatment for acute, painful musculoskeletal conditions. Unlabeled use(s): Treatment of quinine-resistant leg cramps.

 Contraindications Glaucoma; pyloric or duodenal obstruction; stenosing peptic ulcers; prostatic hypertrophy; obstruction of bladder neck; esophageal achalasia; myasthenia gravis.

 Route/Dosage

ADULTS: IV/IM 60 mg q 12 hr prn. PO 100 mg bid.

 Interactions

Alcohol, other CNS depressants: Increased CNS depression. Haloperidol: Worsening schizophrenic symptoms, decreased haloperidol levels, tardive dyskinesia. Phenothiazines: Decreased effects of phenothiazines.

 Lab Test Interferences None well documented.

 Adverse Reactions

CV: Tachycardia; palpitations; transient syncope. CNS: Weakness; headache; dizziness; lightheadedness; confusion (especially in elderly); hallucinations; agitation; tremor; drowsiness. DERM: Hypersensitivity reactions (eg, rashes). EENT: Blurred vision; pupil dilation; increased ocular tension. GI: Dry mouth; vomiting; nausea; constipation; gastric irritation. GU: Urinary hesitancy and retention.

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Elderly patients: May be more sensitive to anticholinergic effects. Cardiac disease: Use drug with caution in patients with cardiac decompensation, coronary insufficiency, cardiac arrhythmias or tachycardia. Heat prostration: Can occur in presence of high environmental temperature. Hypersensitivity reactions: May occur. Sulfite sensitivity: Some products contain bisulfites, which may cause allergic-type reactions in certain persons.

PATIENT CARE CONSIDERATIONS

 Administration/Storage

  • Do not crush or have patient chew sustained-release preparations.
  • Give IV solution over 5 min with patient in supine position. Administer carefully; intoxication is very rapid and can be lethal.
  • Store at room temperature.

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Monitor patient’s vital signs.
  • Monitor blood, urine, and liver function values during long-term therapy.
  • Assess degree of pain relief obtained.
  • Implement safety precautions if patient becomes drowsy or dizzy.
  • Notify physician if rapid heart rate, palpitations, or mental confusion occurs.
  • Carefully document voiding.
OVERDOSAGE: SIGNS & SYMPTOMS
  Cardiac arrhythmias, seizures, coma, shock

 Patient/Family Education

  • Tell patient not to increase dosage of medication. Even slight overdose may be highly toxic.
  • Instruct patient to take sips of water frequently, suck on ice chips or sugarless hard candy, or chew sugarless gum if dry mouth occurs.
  • Advise patient that drug may cause drowsiness or dizziness, and to use caution while driving or performing other tasks requiring mental alertness.
  • Instruct patient to report the following symptoms to physician: Urinary retention, constipation, palpitations, or tremors.
  • Instruct patient to avoid alcohol or other CNS depressants.

Popularity: 2% [?]


If you're still unable to find appropriate information in the article, please use search form below