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(fen-AZZ-oh-PIH-rih-deen HIGH-droe-KLOR-ide)
Azo-Standard, Baridium, Geridium, Prodium, Pyridiate, Pyridium, Pyridium Plus, Urodine, Urogesic, UTI Relief,  Phenazo, Pyronium, Vitoreins
Class: Urinary tract product/Analgesic

 Action Exerts topical analgesic effect on urinary tract mucosa.

 Indications Symptomatic relief of pain, burning, urgency, frequency and other discomforts arising from irritation of lower urinary tract mucosa.

 Contraindications Renal insufficiency.

 Route/Dosage

ADULTS: PO 200 mg tid. CHILDREN (6 to 12 YR): PO 12 mg/kg/24 hr divided into three doses for 2 days.

 Interactions None well documented.

 Lab Test Interferences Possible interference with colorimetric lab test procedures and urinalysis based on spectrometry or color reactions.

 Adverse Reactions

CNS: Headache. DERM: Rash; pruritus. GI: Occasional GI disturbances. GU: Renal toxicity. HEMA: Methemoglobinemia; hemolytic anemia. HEPA: Hepatotoxicity. OTHER: Anaphylactoid reaction.

 Precautions

Pregnancy: Category B. Lactation: Unknown. Renal impairment: May lead to accumulation, indicated by yellow tinge to skin and sclera.

PATIENT CARE CONSIDERATIONS

 Administration/Storage

  • Administer after meals to avoid GI irritation.
  • If patient has renal impairment, dosage reduction may be required.
  • If being taken concomitantly with antibiotics for urinary tract infection, this medicine should be taken for only 2 days (6 doses).
  • Do not crush tablets or make into a suspension.
  • Store at room temperature in a tightly closed container.

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Obtain BUN and creatinine to assess for renal dysfunction.
OVERDOSAGE: SIGNS & SYMPTOMS
  Methemoglobinemia, hemolytic anemia, hemolysis, renal and hepatic impairment and failure

 Patient/Family Education

  • Inform patient that this drug should not be taken long term for undiagnosed urinary tract pain.
  • Advise patient to take drug after meals to avoid GI upset.
  • Inform patient that urine may temporarily become reddish-orange in color and may stain fabric.
  • Advise patient to wear glasses instead of contact lenses while taking this drug; contact lenses may become discolored.
  • Inform patients with diabetes of possible interference with urine glucose test results.
  • Instruct patient not to crush or chew tablets. Permanent teeth discoloration may occur.
  • Instruct patient that if skin or sclera become yellowish in color, to discontinue drug and notify physician.
  • Instruct patient to notify physician if headache, rash, pruritus, upset stomach, dizziness or difficulty breathing occurs.

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